产品货号：
Z17599
中文名称：
HAS2抗体
英文名称：
Anti-HAS2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HAS2 Antibody |
| 指标别名 | hyaluronan synthase 2;HAS2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | IHC |
| 基因名称 | HAS2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals,and is a constituent of the extracellular matrix.It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds.HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane,and the chains are extruded through pore-like structures into the extracellular space.It serves a variety of functions,including space filling,lubrication of joints,and provision of a matrix through which cells can migrate.HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts.Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis.In addition,the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes,and overexpression of HA receptors has been correlated with tumor metastasis.HAS2 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases,and its amino acid sequence shows significant homology to glycosaminoglycan synthetase (DG42) from Xenopus laevis,and human and murine hyaluronan synthase 1. |
| Uniprot ID | Q92819 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | Hyaluronan synthase 2 |
| 推荐稀释比 | Immunohistochemistry in paraffin section IHC-(P) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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